Trevor Bedford

Research Interests

Newton International Fellow studying evolutionary and ecological dynamics of viral pathogens, with particular focus on the influenza virus and its process of antigenic change.

For more information, please go to Trevor's website at www.trevorbedford.com.

Publications

Total publications: 10
Persistent HIV-1 replication maintains the tissue reservoir during therapy.
Lorenzo-Redondo R, Fryer HR, Bedford T, Kim E, Archer J, Kosakovsky Pond, SL, Chung Y, Penugonda S, Chipman JG, Fletcher CV, Schacker TW, Malim MH, Rambaut A, Haase AT, McLean AR & Wolinsky SM (2016) Nature 530, 51-56.
Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone.
Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF & Sabeti PC (2015) Cell 161, 1516-1526.
Global circulation patterns of seasonal influenza viruses vary with antigenic drift.
Bedford T, Riley S, Barr I, Broor S, Chadha M, Cox N, Daniels R, Gunasekaran C, Hurt A, Kelso A, Klimov A, Lewis N, Li X, McCauley J, Odagiri T, Potdar V, Rambaut A, Shu Y, Skepner E, Smith D, Suchard MA, Tashiro M, Wang D, Xu X, Lemey P & Russell C (2015) Nature 523, 217-220.
Reassortment between Influenza B Lineages and the Emergence of a Coadapted PB1-PB2-HA Gene Complex.
Dudas G, Bedford T, Lycett S & Rambaut A (2015) Mol Biol Evol 32, 162-172.
Simultaneously estimating evolutionary history and repeated traits phylogenetic signal: Applications to viral and host phenotypic evolution.
Vrancken B, Lemey P, Rambaut A, Bedford T, Longdon B, Günthard HF & Suchard MA (2015) Methods in Ecology and Evolution 6, 67-82.
The hidden history of HIV-1: establishment and early spread of the AIDS pandemic.
Faria NR, Rambaut A, Suchard MA, Baele G, Bedford T, Ward MJ, Tatem AJ, Sousa JD, Arinaminpathy N, Pépin J, Posada D, Peeters M, Pybus OG & Lemey P (2014) Science 346, 56-61.
Unifying viral genetics and human transportation data to predict the global transmission dynamics of human influenza H3N2.
Lemey P, Rambaut A, Bedford T, Faria N, Bielejec F, Baele G, Russell CA, Smith DJ, Pybus OG, Brockmann D & Suchard MA (2014) PLoS Pathogens 10, e1003932.
Integrating influenza antigenic dynamics with molecular evolution.
Bedford T, Suchard MA, Lemey P, Dudas G, Gregory V, Hay AJ, McCauley JW, Russell CA, Smith DJ & Rambaut A (2014) eLife 3, e01914.
Canalization of the evolutionary trajectory of the human influenza virus.
Bedford T, Rambaut A & Pascual M (2012) BMC Biol 10, 38.
Improving the accuracy of demographic and molecular clock model comparison while accommodating phylogenetic uncertainty.
Baele G, Lemey P, Bedford T, Rambaut A, Suchard MA & Alekseyenko AV (2012) Mol Biol Evol 29, 2157-2167.
 
Andrew Rambaut, 2007